BENZENE


Benzene is one of the most fascinating molecules. The structure of this molecule eluded chemists until 1865 when Friedrich August Kekulé proposed that it consisted of a hexagonal ring with a carbon atom at each vertex. Every student of Organic Chemistry has heard the story of how the structure appeared to Kekulé in a dream in which he saw chains of carbon atoms dancing in circles like a snake chasing its own tail.

Alas, benzene is both toxic and carcinogenic. In fact, it might be considered "the mother of all carcinogens," as a large number of carcinogens have structures that include benzene rings. (See the link below for the explanation of this.) I recall my Organic Chemistry professor joking about how he used to "practically bathe in benzene up to the elbows" when he would use it in his research (presumably before it was identified as a carcinogen). He predicted that this would probably lead to his demise. He was right--he died due to leukemia several years ago.


The Structure of Benzene:



3-D Ball and Stick Model:



3-D Space-Filling Model:



Links to More Information About Benzene:

Lecture Notes on Benzene from Chem 7 at UCSC

Polycyclic Aromatic Hydrocarbons and Cancer

Agency for Toxic Substances and Disease Registry